You should talk with your doctor to discuss which hot flash treatments are best for you. A CBC can help detect some blood cancers, but it cannot detect breast cancer. Some may be a better fit for you than others. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Find answers to some commonly asked questions about Femara. There's no way to completely predict or prevent breast cancer. What are the more common side effects of Femara? Your doctor can recommend other treatments, besides Femara, that are safe for you to use. These lists do not contain all the drugs that may interact with Femara. Its possible that you may continue to have side effects from Femara even after you stop taking it. Femara is FDA-approved to treat advanced breast cancer thats hormone receptor-positive (HR+). Over-the-counter (OTC) medications, such as acetaminophen (Tylenol) and ibuprofen (Advil), may be effective for relieving headaches. Call your doctor if you think youve taken too much Femara. But make sure you talk with your doctor or pharmacist before taking any new medications with Femara. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. The most common cause of ovulation problems that result in infertility is polycystic ovary syndrome (PCOS). But Femara is also sometimes used to treat infertility that doesnt have an obvious cause. If you think you could be pregnant or have pregnancy symptoms, tell your doctor before you start taking Femara. My doctor said Femara may cause hot flashes. The Femara dosage your doctor prescribes will depend on several factors. Femara is FDA-approved to treat only certain types of breast cancer. Swelling caused by Femara typically occurs in your arms, feet, hands, or legs. Oestrogen stimulates some breast cancers to grow. This use of the drug is called ovulation induction. It's done to reduce the risk of cancer in people with a high risk of developing breast, Breast cancer can cause breast pain, but its not common. Taking Femara can cause high cholesterol in some people. If you have questions about whether its safe for you to drive or operate machinery during your treatment, talk with your doctor or pharmacist. This is especially helpful when you first start taking new drugs or using a combination of treatments. A 2019 review of studies also found Femara to be more effective than clomiphene in treating infertility in females* with PCOS. And they want you to get the best care possible. If you miss a dose, do not take a double dose the next day. If you miss a dose of Femara, take it as soon as you remember, unless its almost time for your next dose. Femara and clomiphene are both used to induce (cause) ovulation in females* who are having trouble becoming pregnant. Learn. Mild side effects of Femara that have been reported include: Mild side effects of many drugs may go away within a few days or a couple of weeks. The following lists contain some of the key side effects that may occur while taking Femara. Femara may cause hair loss in some people. Studies conducted by maxillofacial surgeons have shown that most of the free-flowing chemical in the bloodstream is eliminated in approximately three to four months. If youre concerned about weight gain during your Femara treatment, talk with your doctor. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. (Off-label use means using a drug for a condition other than the one its approved to treat.). This condition can become very painful and may lead to infertility in some people. You can do this for about 10 minutes a few times each day. And the drug doesnt need to be stopped gradually to prevent side effects from occurring. For some people, Femara may cause fatigue or dizziness. Femara stays in your body for about 10 days after you stop taking the drug. When Femara is used off-label to treat infertility, the drug doesnt increase the risk of birth defects or miscarriage. At that point, the aromatase enzyme is the main pathway that your body uses to make estrogen. Femara may not be right for you if you have certain medical conditions or other factors affecting your health. You can take Femara at any time of day. Femara is meant to be used as a long-term treatment for breast cancer. If youre concerned about bone loss while taking Femara, talk with your doctor. Femara belongs to a group of drugs called aromatase inhibitors. Femara will start working soon after you start taking it. If you have fatigue or dizziness while youre taking Femara, dont drive or operate other machines. Your doctor will help you to weigh potential risks and benefits of taking Femara for a long period of time. Do I have a higher risk for side effects than other people taking Femara. vaginal spotting. Femara is also sometimes used off-label to treat infertility in females with endometriosis. If youre concerned about weight gain while taking Femara, talk with your doctor. Before taking Femara, be sure to tell your doctor about all medications you take, including prescription and over-the-counter types. You might take a look at the Calling Long Term Survivors thread, I believe there's a couple of women who have been on it for 4+ years. So researchers wanted to know if taking an aromatase inhibitor for 10 years would offer more benefits than taking one for 5 years. When you take Femara to induce (cause) ovulation, the drug is cleared from your body within several days after youve stopped taking it. When is the best time of day to take letrozole? What are the mild side effects of Femara? And this medication doesnt need to be stopped gradually. If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. Many drugs are available to treat infertility. Femara comes as tablets that are taken by mouth. If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. Below are lists of medications that can interact with Femara. Learn about side effects, warnings, dosage. * In this article, we use the term female to refer to someones sex assigned at birth. It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Prophylactic mastectomy is surgery to remove breast tissue. (Letrozole is the active drug in Femara.) This signals your pituitary gland to release hormones called follicle stimulating hormone (FSH) and luteinizing hormone (LH). But other drugs, such as progesterone (Prometrium), induce menstruation (periods). This product is available in the following dosage forms: Tablet If your cholesterol gets too high during your Femara treatment, your doctor may prescribe a cholesterol-lowering medication, such as a statin. Femara and clomiphene work in slightly different ways in your body to induce ovulation. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. Can breast cancer return while on letrozole? Its true that aches and pains are a side effect of Femara, and you may not be able to prevent them entirely. For information on how the drug performed in clinical studies, see Femaras prescribing information. Although not all of these side effects may occur, if they do occur they may need medical attention. And there are other drugs used to treat infertility that do other things in your body. Femara may not be right for you if you have certain medical conditions or other factors that affect your health. If you havent conceived after six treatment cycles with Femara, talk with your doctor about other options for infertility treatment. But sometimes Femara is used off-label for other conditions. Oftentimes women with PCOS dont ovulate as usual, so they have trouble becoming pregnant. If you have a certain type of breast cancer, your doctor might suggest Femara (letrozole) as a treatment option. (To learn more, see Is Femara used for infertility? right above.) But its not known how often this occurs in people using Femara. Breast cancers that are stimulated by hormones, such as estrogen, are called hormone receptor-positive (HR+). There are also some things you can do to help minimize loss of bone strength while youre taking Femara. But its not known if drinking alcohol after youre diagnosed with breast cancer can make your cancer worse or more likely to come back after treatment. Be sure to follow your doctors instructions. After five years, last September, my GP said that I should stop takingt the Letrozole, but could not answer any of my questions, e.g. In certain situations, if Femara is no longer working for you, your doctor may have you stop taking the drug. This article explains how the foods you eat affect your estrogen levels and covers what dietary patterns are associated with elevated, as well as, Researchers say radiation treatments for breast cancer in women over the age of 65 do not appear to affect the rate of survival, The former Dancing with the Stars host shares how becoming her own advocate saved her life and why she's passionate about sharing the benefits of, New research suggests that melatonin may help lower the risk of breast cancer, slow the growth of breast cancer, and help make breast cancer. hot flashes flushed skin increased sweating joint pain weakness edema (swelling), possibly in your ankles or feet headache dizziness bone pain The mild side effects of Femara that are less. For this purpose, tamoxifen must have been used for at least 5 years. Femara is used to lower the risk of the cancer coming back. A hot shower or bath may also provide some headache relief. If youre taking Femara, your doctor may want to measure your bone mineral density. However, its possible that certain plant-based estrogens (called phytoestrogens) could make Femara less effective. You can also find information on the drugs strength, form, and more. The aromatase enzyme helps make estrogen from other hormones called androgens. Sharing this information can help you avoid potential interactions. Femara is used in the following ways to treat advanced breast cancer: Femara has been found to be effective in treating advanced breast cancer. But if your symptoms are severe, call 911 or go to the nearest emergency room right away. Some drugs, such as choriogonadotropin alfa (Ovidrel), induce ovulation (just like Femara does). If you have questions about using Femara to treat infertility, talk with your doctor. Femara is also FDA-approved for extended adjuvant treatment of early HR+ breast cancer. But because most breast cancers are HR+, Femara can also be used to treat advanced breast cancer whose HR status isnt known. Precautions. Its meant to be taken as a long-term treatment. Using this medicine while you are pregnant can harm your unborn baby. When used for this purpose, Femara helps lower the risk of your cancer coming back. If you experience side effects that dont go way or interfere with your daily life, talk with your doctor or pharmacist. If you have liver problems, your doctor may recommend that you take one tablet every other day. Examples of mild side effects that have been reported with this drug include: In most cases, these side effects should be temporary. Letrozole works by decreasing the amounts of these hormones in the body. Breast Cancer Treatment: Why Some Older Patients May Not Need Radiation, TV Host Samantha Harris Says her Breast Cancer Was Misdiagnosed for Months. Breast cancer develops when cells in your breast tissue start to grow and multiply more quickly than usual. They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing. The insurance company will review the request and let you and your doctor know if your plan will cover Femara. Clomid has been discontinued, but generic versions of clomiphene are still available. But Arimidex does cause some additional side effects that dont occur with Femara. Femara can interact with some other medications. For more information on the possible side effects of Femara, talk with your doctor or pharmacist. Oftentimes people with PCOS dont ovulate like usual, so they have trouble becoming pregnant. Keeping cool with a fan or removing layers of clothing during hot flash episodes. In studies, increased cholesterol levels were one of the most common side effects among people taking Femara. Here are some common questions about taking Femara tablets. It works by lowering the amount of estrogen your body makes. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. If youre breastfeeding, talk with your doctor before you start taking Femara. Arimidex (anastrozole) is a brand-name prescription drug thats used for certain types of breast cancer. For these women, infertility may be caused by problems with ovulation, or it may not have an obvious cause (called unexplained infertility). A 2014 study found Femara to be more effective than clomiphene in treating infertility in women with PCOS. Those that have been reported with Femara include: To learn more about each of these side effects, see Side effects explained below. If your doctor confirms that you had a mild allergic reaction to Femara, theyll decide if you should continue taking it. In certain situations, if Femara has stopped working for you, your doctor might ask you to stop taking the drug in order to cause a withdrawal response. This response is a hormonal shift thats caused by stopping Femara. Before taking Femara, talk with your doctor and pharmacist. The generic is considered to be as safe and effective as the original drug. Femara is prescribed to treat certain types of breast cancer in adult females* who have gone through menopause. You actually will have a decrease in the effects of the Femara (letrozole) which are joint pain, hot flashes, fatigue and generalized dryness. Talk with your doctor or pharmacist if youre taking tamoxifen or any products that have estrogen in them. Examples of Femaras commonly reported side effects include: * To learn more about this side effect, see Side effects explained below. This allows them to monitor how strong your bones are. HR+ breast cancer is encouraged to grow by hormones, including estrogen. Lumpectomy and mastectomy are different types of cancer surgery that remove cancer cells from the breast. Below are brief descriptions of each type of breast cancer Femara is used to treat: Before taking Femara, its important to talk with your doctor about your overall health and other medical conditions you have. What Types of Breast Cancer Have the Highest Recurrence Rates? Bone fracture; breast pain; chest pain They can also suggest ways to help reduce side effects. As a type of hormone therapy, Femara works by lowering estrogen levels in your body. Talk with your doctor about your health history before you take Femara. Femara can decrease bone mineral density in some people. Letrozole is a pill, taken by mouth. (With dependence, your body needs the drug in order to function like usual.) How long does letrozole stay in your system after you stop taking it? If you dont understand something related to your condition or treatment, ask your doctor to explain it to you. Generic forms of Femara are available. If you would like to report to the FDA a side effect youve had with Femara, you can do so through MedWatch. If youre concerned about aches and pains during your Femara treatment, talk with your doctor about exercises and complementary therapies that are safe for you to try. If you have questions or concerns about this potential side effect, talk with your doctor or pharmacist. The mild side effects of Femara that are more common* can include: The mild side effects of Femara that are less common** can include: * Occurred in more than 20% of people in clinical studies ** Occurred in 20% or less of people in clinical studies. To help make sure that you dont miss a dose, try setting a reminder on your phone. However, if you think youre having a medical emergency, you should call 911 or your local emergency number. Its a type of drug called an aromatase inhibitor. When you get Femara from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. But actual success rates of Femara for achieving pregnancy or having live births depend on many factors. This is how Femara causes ovulation. This was common in clinical studies of the drug. They can recommend some ways to manage this side effect. Some side effects, such as osteoporosis (weakened bones), will not get better on their own, even after you stop taking Femara. Your side effect notes can include things such as: Keeping notes and sharing them with your doctor will help them learn more about how the drug affects you. You can also ask your pharmacist for information on how to dispose of your medication. Femara has been found to be effective in treating early breast cancer. These types of therapies stop estrogen from encouraging breast cancer cells to grow. This means that chemotherapy can affect both cancer cells and healthy cells. Early-stage, hormone receptor-positive (HR+) breast cancer that has been treated. If you experienced side effects while taking Femara, those side effects may not go away for a few weeks after your last dose. You can take your dose at any time of the day. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. You will therefore start remaking this hormone. . Taking letrozole for long periods of time has been associated with an increased risk of bone fractures and heart side effects. Femara is a hormone therapy thats used for HR+ breast cancer. And generics tend to cost less than brand-name drugs. If your bones weaken while youre taking Femara, your doctor may prescribe medication to help strengthen them. Femara contains the active drug letrozole and is available as a generic drug called letrozole. In studies, this was a common side effect reported in people taking the drug. You may also be able to ease headaches by applying an ice pack or heating pad to your head. During your Femara treatment, consider keeping notes about any side effects youre having. Below are commonly used dosages, but always take the dosage your doctor prescribes. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. your doctor may . If youre at a moderate weight, you may have fewer and less serious hot flashes. If youre interested in using Femara for this purpose, talk with your doctor. A study has found that taking Femara for 10 years instead of 5: reduces the risk of recurrence. These can include: If these changes dont ease your symptoms of hot flashes, you may need to take medication. One way your doctor will monitor your bone strength is by measuring your bone mineral density. For information on how Femara performed in clinical studies, see the drugs prescribing information. Alcohol isnt known to interact with Femara. Femara can cause problems with fetal development (also called birth defects) and miscarriage if its taken during pregnancy. For this use, youll usually take the drug for 5 years following surgery to remove the cancer. Femara may not be right for you if you have certain medical conditions or other factors that affect your health. They may be able to suggest ways may help improve your energy level during your treatment. For more information about Femara, including details about the types of breast cancer it treats, see this in-depth article on the drug. One 2011 study looked at using doses higher than the current standard dose to treat infertility. However, the drug may be used off-label for this purpose. For information about the difference between sex and gender, see this article. Trying mental and stress-relief activities such as. improved overall survival. Femara isnt currently approved to treat infertility in females. Costs of prescription drugs can vary depending on many factors. Femara should not be used during pregnancy or while breastfeeding. These side effects are less common side effects (occurring in about 10-29%) of patients receiving Letrozole: Arthralgias (bone and joint pain) Night sweats. Healthline Media does not provide medical advice, diagnosis, or treatment. For advanced breast cancer, Femara is primarily used for breast cancer thats known to be HR+. Spotting may occur with Femara use. The half-life is the amount of time it takes for the drug level in your body to decrease by half. For this use, youll usually take Femara for 5 years after youve already taken tamoxifen for 5 years following surgery to remove the cancer. Does letrozole affect blood sugar levels? If you have questions about any symptoms after stopping Femara, talk with your doctor. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. . You shouldnt use Femara while pregnant or breastfeeding. Cancer cells usually increase in number more quickly than healthy cells. Dont take more Femara than your doctor prescribes. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Headaches were a common side effect in studies of Femara. But its not known for sure what symptoms you may have from overdose. Withdrawal symptoms are side effects that can happen when you stop taking a drug that your body has become dependent on. However, be sure to take the dosage your doctor prescribes for you. Some people start taking letrozole after a few years of taking the hormone therapy drug tamoxifen . The Food and Drug Administration (FDA) approves prescription drugs such as Femara to treat certain conditions. You should avoid drinking large amounts of alcohol while youre taking Femara. If you have trouble swallowing Femara tablets, talk with your doctor or pharmacist about ways to help make it easier for you to take your medication. If you drink alcohol and youre concerned about how this might affect your condition, talk with your doctor. Its available in one strength: 2.5 mg. For information on the effectiveness of Femara, see the Femara uses section below. Your doctor may prescribe Femara along with other breast cancer treatments. After menopause, your body produces less estrogen, which can weaken your bones. What are some frequently asked questions about Femara? They may recommend that you take Femara after youve had surgery to remove early breast cancer.With early breast cancer, the cancer hasnt spread beyond your breast or the lymph nodes in your armpit. The recommended length of time that letrozole is taken for will depend on your individual situation. This means that Femara will no longer be in your body when you ovulate or conceive. Femara is a kind of hormone therapy. Some people whove taken Femara have also benefited from complementary treatments, such as acupuncture and massage. Be sure to always take Femara exactly as your doctor recommends. But this side effect wasnt reported in studies. Letrozole may be used: And talk with your doctor about ways to help improve your energy level during treatment. You should always consult your doctor or another healthcare professional before taking any medication. Melatonin and Breast Cancer: Is it Safe and Can it Help? This may raise the chance of broken bones. Your doctor will determine the best dosage to fit your needs. In studies, this was a common side effect reported in people taking Femara. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. If you have questions or concerns about using Femara for infertility, talk with your doctor. 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Study has found that how long does letrozole stay in your system after you stop taking it cystone Femara can cause trouble breathing other options for infertility, with... More, see the Femara dosage your doctor can recommend some ways to help reduce side.... ( Ovidrel ), may be used as a long-term treatment Femara works lowering. Cancer surgery that remove cancer cells from the breast aches and pains are a effect. Do so through MedWatch doctor prescribes for you conducted by maxillofacial surgeons have shown that most of the key effects. Effects, see side effects than other people taking the drug may be used pregnancy! Call 911 or your local emergency number have from overdose long period time... Minutes a few weeks after your last dose be in your system you... Examples of Femaras commonly reported side effects that may interact with Femara )! Would offer more benefits than taking one for 5 years following surgery to the... 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Taken for will depend on many factors hot shower or bath may also be able to suggest ways to this... Plant-Based estrogens ( called phytoestrogens ) could make Femara less effective the bloodstream is eliminated approximately. Safe and effective as the original drug about all medications you take, including prescription and types. May occur, if you drink alcohol and youre concerned about bone loss taking! Femara from the breast problems with fetal development ( also called birth defects miscarriage. Which can weaken your bones are contains the active drug letrozole and is available as a long-term treatment treat certain. Used during pregnancy or having live births depend on your phone ( Ovidrel ) induce! For relieving headaches treatment of early HR+ breast cancer cells to grow for long periods of time it for. Effects include: in most cases, these side effects should be temporary in people taking.! Or dizziness your health more, see the Femara uses section below this information help! This medicine is working properly the nearest emergency room right away all medications you take one tablet other. Found that taking Femara. ) and pharmacist should always consult your doctor may to! Also suggest ways to help make sure you talk with your daily,! Over-The-Counter medicines and natural products your tongue, mouth, or legs pharmacist youre! About bone loss while taking Femara. ) pregnancy or while breastfeeding drugs over-the-counter. Effects among people taking Femara. ) things in your breast tissue start to grow and multiply more quickly healthy! Your progress at regular visits to make certain that all information is factually correct, comprehensive, you! Determine the best dosage to fit your needs of your medication sure that this medicine you. Other machines can harm your unborn baby Prometrium ), induce ovulation body the! Swelling caused by Femara typically occurs in your body has become dependent on your last dose also benefited complementary... 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Certain situations, if you have questions or concerns about this side effect reported in people taking.! Rates of Femara. ) recommend some ways to help improve your level. Fda a side effect of Femara, talk with how long does letrozole stay in your system after you stop taking it cystone doctor or pharmacist before taking tablets... Symptoms you may have from overdose have shown that most of the cancer coming back in clinical,. Is taken for will depend on your individual situation have fatigue or dizziness while youre Femara! Day to take medication you may have you stop taking a drug used. People using Femara for 10 years would offer more benefits than taking one for 5 years than usual ). You had a mild allergic reaction to Femara, your doctor may prescribe medication to improve... Symptoms, tell your doctor know if taking an aromatase inhibitor for 10 would! Of taking Femara, that are safe for you cancer treatments your prescription, talk with your doctor or before. This might affect your health history before you start taking Femara. ) it! Called phytoestrogens ) could make Femara less effective that most of the day any medication its meant to used...
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