, Chen, Zhong, Chunpeng Zhang, Dayong Wu, Hongyan Chen, Anna Rorick, Xiaoting Zhang, and Qianben Wang. A Duke alumni couple has made an anonymous bequest of $15 million to Duke, most of which will support scholarships for students pursuing degrees at Liked by Jianyin Wang , Agoulnik, Irina U., William E. Bingman, Manjula Nakka, Wei Li, Qianben Wang, X Shirley Liu, Myles Brown, and Nancy L. Nancy L. , Bao, Bo-Ying, Bin-Fay Chuang, Qianben Wang, Oliver Sartor, Steven P. Balk, Myles Brown, Philip W. Kantoff, and Gwo-Shu Mary Lee. xb```f``x(P%(U| The title of his talk was Identifying and targeting poorly druggable factors in hormone-dependent cancers and COVID-19. Our results reveal a novel role of MED1 in Pol II transcription and identify phosphorylated MED1 as a targetable driver of dysregulated Pol II recycling in cancer. Dr. Qianben Wang earned his Ph.D. in 2002 from the University of Maryland School of Medicine under the supervision of Dr. Joseph Fondell. Our paper entitled Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer was published by Cell as the Featured Article. Zhongs paper entitled Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling was accepted by Nature Communications. Qianben was invited to present on The 12th National Symposium on Prostate Cancer and Dr. Sidney A. McNairy Jr. Student Symposium in Atlanta, GA. Qianben was invited to present on 2018 Duke Basic Science Day: Genomic Determinants for Andorgen Receptor-V7 Oncogenic Function in Castration-Resistant Prostate Cancer.. Dynamic ChIP-seq confirmed PAF1 silencing triggered defective Pol II recycling in human cells. If you see a problem with the information, please write to Scholars@Duke and let us know. 15 0 obj <> endobj Qianyuan Wu's 20 research works with 239 citations and 1,335 reads, including: Highly Selective Production of Singlet Oxygen by Manipulating the Spin State of Single-Atom Co-N Moieties and . The project is entitled Novel Tumor Suppressive Role of Phosphodiesterases in Prostate Cancer. The oncogenomic function of androgen receptor in esophageal squamous cell carcinoma is directed by GATA3. If left unofficial, the government cannot be held responsible. , Xu, Lingfan, Yu Yin, Yanjing Li, Xufeng Chen, Yan Chang, Hong Zhang, Juan Liu, et al. Free Speech Debate is a research project of the Dahrendorf Programme for the Study of Freedom at St Antony's College in the University of Oxford. Dr. Wangs laboratory is primarily interested in understanding the transcriptional and epigenetic mechanisms driving progression of hormone-dependent cancers as well as the role of host proteases in coronavirus infection. Dr. Wangs laboratory is primarily interested in understanding the transcriptional and epigenetic mechanisms driving progression of hormone-dependent cancers as well as the role of host proteases in coronavirus infection. He conducted his postdoctoral training in Dr. Myles Brown's lab at Dana-Farber Cancer Institute, Harvard Medical School. Nucleosome dynamics define transcriptional enhancers. Wang Qianyuan Written in the early morning of 10 April 2008 . He won Best Actor at the 23rd Tokyo International Film Festival for his role in the movie, The Piano in a Factory . She graduated from the University of Peking in 1903 and then worked as a teacher before becoming a politician. In the Mao era this was very common practice. 2023 Please read them with this in mind. , Huang, Furong, Hongyan Chen, Xiaolin Zhu, Tongyang Gong, Xukun Li, William Hankey, Hongyan Wang, Zhong Chen, Qianben Wang, and Zhihua Liu. Lisa Yee and Qianben Wang) earned his PhD upon successful defense of his thesis entitled Methylome analysis: From computation workflow development to implementation in a breast cancer prevention trial. His current research focuses on studying the epigenetic mechanisms underlying the hormone-dependent cancers. The article has been selected by the editors of Nucleic Acids Research as a Breakthrough Article. 0000001083 00000 n Jones argues that the Ukrainian state should not restrict open historical debate but use its 'expressive' powers to foster a nuanced understanding of the past. December 2013 No Fun to Be a Traitor" were painted on the outside wall of Wang's apartment. , Chen, Zhong, Xun Lan, Dayong Wu, Benjamin Sunkel, Zhenqing Ye, Jiaoti Huang, Zhihua Liu, Steven K. Clinton, Victor X. Jin, and Qianben Wang. Tim Huang, Victor Jin and Qianben Wang were awarded a five-year Multi-PI NCI U54 center grant totaling $9.12 million entitled Systems Analysis of Epigenomic Architecture in Cancer Progression. Suite C. St. Louis, MO 63128. "This is a major breakthrough . , Ye, Zhenqing, Zhong Chen, Xun Lan, Stephen Hara, Benjamin Sunkel, Tim H-M Huang, Laura Elnitski, Qianben Wang, and Victor X. Jin. The multinational advertising agency he and his girlfriend worked for, Saatchi & Saatchi, issued a statement reporting that they both had voluntarily resigned, but Wangs lawyer says they were forced to resign and went into hiding. January 2016 Dietary omega-3 fatty acid intake impacts peripheral blood DNA methylation -anti-inflammatory effects and individual variability in a pilot study. By what name was Caught in Time (2020) officially released in India in English? Of interest is the emerging role of fatty acids to impact DNA methylation (DNAm) and thereby modulate mediating inflammatory processes. Reported by Duke Pathology News: Yuan Receives DoD Early Investigator Research Award.. Contact the Duke WordPress team. Will it work in people? Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection. We show that this nanosystem decreases lung Ctsl expression in normal mice efficiently, specifically and safely. 0000001508 00000 n Phospho-MED1-enhanced UBE2C locus looping drives castration-resistant prostate cancer growth. *also carried by The Herald Sun, The Seattle Times,The Miami Herald,Phys.org, andAOL, MedicalXpress.com:CRISPR technology demonstrates success in preventing and treating COVID, News Medical Life Sciences: Using CRISPR technology to successfully prevent and treat SARS-CoV-2 infections, Duke University SOMNewsRoom:CRISPR Technology Demonstrates Success in Preventing and Treating COVID. , He, Huiling, Wei Li, Sandya Liyanarachchi, Mukund Srinivas, Yanqiang Wang, Keiko Akagi, Yao Wang, et al. Reported by Duke Pathology News: Staats Lab Receives NIH Funding for Adjuvant Comparison Contract., The Telegraph (UK): Taking a puff on a new inhaler can stop you getting COVID, *also carried by New Zealand Herald, Durham Reporter: Duke Med researcher on new COVID approach:This is just to prevent the virus to enter the cell, WAVY NBC-10: Prepping treatments for COVID regardless of mutation (*clip begins @ 04:46:00), *also carried by WVBT FOX-43, Norfolk. Phone (636) 489-1602 . Qianben Wang, Victor Jin and Nameer Kirma co-organized a one-day San Antonio-Duke Cancer Systems Biology Symposium, Modeling and Interrogation of Hormone-Independent Cancer Progression at the University of Texas Health San Antonio campus. DNA methylation of PBMCs was assayed by reduced representation bisulfite sequencing (RRBS) to obtain genome-wide methylation profiles at the single nucleotide level. One of the best known examples is a video that emerged in 2006 of a woman kicking a kitten to death in her stilettos while a friend filmed her. Huang receives DoD prostate cancer research award., Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling, Our PDE5i research was selected by Department of Defense (DoD) Prostate Cancer Research Program as a 2021 Research Highlight, San Antonio-Duke University Research Center for Cancer Systems Biology. The title of his talk was Epigenetic regulation in hormone-dependent cancers. RNA Polymerase II (Pol II) transcriptional recycling is a mechanism for which the required factors and contributions to overall gene expression levels are poorly understood. . New Apple Originals every month. He said he does not need police protection," said Liu Guoxiang, a police officer in the Qingdao Public Security Bureau. HW]s}#~dzvf;igDB$?)[;eF{lgn~X[&N(aOIT+,\7}'bnn0k1aMo?%NVw:2{:2I? qJ"=ocNH* Contact the Duke WordPress team. Duke University Congratulations, Bill !! Alternative polyadenylation of mRNA and its role in cancer. PBMCs of women at high risk of breast cancer (n=10) were obtained at baseline and after 6 months of n-3 PUFA (5 g/d EPA+DHA dose arm) intake in a previously reported dose finding trial. 0 A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer. Wang, a human resource manager in a cargo tally company under the Qingdao Bureau of Port Affairs in Shandong Province, has shunned contacts with the outside. Please read the Duke Wordpress Policies. Mechanistically, MED31 mediates the recycling of phosphorylated MED1 and Pol II, enhancing mRNA output during the transcription recycling process. In conjunction with the NCI visit to the San Antonio-Duke University Research Center for Cancer Systems Biology on April 19th, 2019, Drs. Prostate Cancer Cell Phenotypes Remain Stable Following PDE5 Inhibition in the Clinically Relevant Range. Qianyuan Wang was born on June 23, 1972 in Shenyang, Liaoning, China. August 2010 Our invited review article entitled Androgen receptor-driven chromatin looping in prostate cancer was published in Trends Endocrinol Metab. Helen Haft explains how the Orthodox Church has eroded freedom of the media and lobbied for the 2013 law against offending religious feelings. Watch on Apple devices, streaming platforms, and smart TVs. With Qianyuan Wang, Daniel Wu, Jessie Li, Michelle Wai. 7 times. Fuwen Yuan from Peking University joined the lab as a postdoctoral fellow. The New York Times even refers to human flesh searches as Red Guards 2.0. We will reply promptly. Chromatin-associated APC regulates gene expression in collaboration with canonical WNT signaling and AP-1. Arthur Stockwin explains the four main areas where free speech is under threat in Japan. , Cai, Changmeng, Hongyun Wang, Housheng Hansen He, Sen Chen, Lingfeng He, Fen Ma, Lorelei Mucci, et al. We describe an in vitro methodology facilitating unbiased identification of putative RNA Pol II transcriptional recycling factors and quantitative measurement of transcriptional output from recycled transcriptional components. Kaifu and Zhongs paper entitled Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes. was accepted by Nature Genetics. Wang Qianyuan is a Chinese actor who graduated from the Central Academy of Drama. , Zhang, Mei, Parmeet K. Manchanda, Dayong Wu, Qianben Wang, and Lawrence S. Kirschner. On 29 December 2008 he was dismissed from office and in February 2009 a formal investigation for bribery and gross violation of party discipline began. Contact the Duke WordPress team. Qianben received an OSU Pelotonia Idea Grant with our Co-PI, Dr. Steven Clinton. Qianyuan was born in 1881, in Shaanxi, China. Yuan Wang Assistant Professor of International Relations at Duke Kunshan University Current Appointments & Affiliations Assistant Professor of International Relations at Duke Kunshan University, DKU Faculty , Duke Kunshan University 2022 Assistant Professor of the Practice, DKU Visiting Faculty , Duke University 2022 Contact Information [email protected]. Our collaborative paper with Victor Jin lab entitled . On 10 December 2008 he told local media that any developer selling property below its actual cost would be prosecuted a very sensitive issue in China given the high property prices. November 2011 experienced the wrath of human flesh searchers, explained in Shanghais Oriental Morning Post. An accounting firm where Wang's mother Han Yunzhi had worked before 2006 has also been bothered with protesting phone calls. Welcome! Interestingly, we observe dynamic switches among nucleosome states upon androgen stimulation, accompanied by distinct differential (gained or lost) binding of FOXA1, GATA2, H1 as well as many other coregulators. Ben was awarded a Ruth L. Kirschstein National Research Service Award (NRSA, F31) from the NIH/NCI. July 2011 Furong received his B. Med. In online forums or bulletin boards, netizens search for and share information to identify an individual, their whereabouts, personal and contact details. Zhifens paper entitled Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection was accepted by Nature Chemical Biology. Room 1027A, Gsrb1, Box #103864,, Durham, NC 27710 Contact Contact Us 888-ASK-DUKE (888-275-3853 . Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Qianben was invited to serve on the School of Medicine Clinical Sciences Appointment, Promotion, and Tenure Committee at Duke University. Conducted interviews with senior executives and negotiated with general counsel during due diligence of a $200M business process . Our work offers structural and mechanistic insight into the dynamics of pioneer factors governing nucleosome reorganization. Qian-Yuan Wu Removal of trace organic contaminants (TOrCs) is important for treatment of contaminated water and decreasing the associated risks. Phosphorylated MED1 links transcription recycling and cancer growth. Dr. Wang joined the Department of Pathology at Duke University School of Medicine as a Professor with tenure in December, 2017. Powered by VIVO, Jeon, Hee-Young, Majid Pornour, Hyunju Ryu, Sudeep Khadka, Rui Xu, Jihyun Jang, Deqiang Li, et al. xref We will work with Dr. Wei Li (PI) to study alternative polyadenylation by using computational and experimental modeling. , Li, Yanjing, Yiping He, William Butler, Lingfan Xu, Yan Chang, Kefeng Lei, Hong Zhang, et al. Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro. , Chen, Zhong, Zhenqing Ye, Raymond E. Soccio, Tomoyoshi Nakadai, William Hankey, Yue Zhao, Furong Huang, et al. Qianyuan Wang was born on 23 June 1972 in Shenyang, Liaoning, China. Dr. Qianben Wang earned his Ph.D. in 2002 from the University of Maryland School of Medicine under the supervision of Dr. Joseph Fondell. Highest Rated: 100% Saving Mr. Wu (2015) Lowest Rated: 88% The Eight Hundred (2020) Birthday: Jun 23, 1972. Netizens started a human flesh search and threatened her so that she was taken in by the police for protection due to the high number of death threads she received. from Shanghai Normal University (Joint training with Shanghai Institute of Applied Physics) and Ph.D. in Inorganic Chemistry from University of the Chinese Academy of Sciences. September 2012 Swipe left to browse all of the highlights. Reported by Duke Center for Applied Genomics & Precision Medicine: New Postdoc fellows ready to dive into genomic research. Atomically dispersed CuN4 moieties were confirmed by hi Welcome to Qianben Wangs laboratory. WIKIPEDIA. https://scholars.duke.edu/individual/pub1515961. Zhongs paper entitled Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer was accepted by EMBO J. July 2014 University of Texas Health Science Center at San Antonio. , Chen, Hongyan, Jianlin Ma, Benjamin Sunkel, Aiping Luo, Fang Ding, Yi Li, Huan He, et al. Center PIs presented project progress at the virtual meeting. As Rebecca MacKinnon points out, there is a strong tradition in China of setting the masses on local officials to fight corruption. Protesting words such as "Wake up. Qianben served as a co-chair of the Nuclear Receptor Function and Co-factors session of the Gordon Research Conference on Hormone-Dependent Cancers (Newry, Maine). View the profiles of professionals named "Qianyuan Wang" on LinkedIn. They have also maintained "hotline contacts" with the residential committee and Wang's close neighbors for clues of harassment. , Cui, Zhifen, Cong Zeng, Furong Huang, Fuwen Yuan, Jingyue Yan, Yue Zhao, Yufan Zhou, et al. We further show that this approach extends survival of mice lethally infected with SARS-CoV-2, correlating with decreased lung virus burden, reduced expression of proinflammatory cytokines/chemokines and diminished severity of pulmonary interstitial inflammation. Han, who is not a native of Qingdao, has not been seen at the apartment for a long time. SARS-CoV-2 entry into cells requires specific host proteases; however, no successful in vivo applications of host protease inhibitors have yet been reported for treatment of SARS-CoV-2 pathogenesis. Qianben Wang, Jiaoti Huang, and Steven Clinton were awarded a Multi-PI NCI R01 grant entitled Role of oncogenic phosphorylated MED1 in aggressive prostate cancer. Dating & Relationship status He is currently single. from Capital University of Medical Sciences and M.S. He is an actor, known for Saving Mr. Wu (2015), The Piano in a Factory (2010) and The Big Shot (2019). 15 13 Both were identified within a day and bombarded with telephone calls. After trying to mediate between Chinese students and Free Tibet groups on campus, a video of her appeared online and she was branded a "race traitor" to the Chinese people. 22 Qianyuan Wang pictures. 0000002633 00000 n The title of his talk was Epigenetic and transcriptional regulation in hormone-dependent cancers. endstream endobj 16 0 obj<> endobj 17 0 obj<> endobj 18 0 obj<>/Font<>/ProcSet[/PDF/Text]/ExtGState<>>> endobj 19 0 obj<> endobj 20 0 obj<> endobj 21 0 obj[/ICCBased 26 0 R] endobj 22 0 obj<> endobj 23 0 obj<> endobj 24 0 obj<> endobj 25 0 obj<>stream Local authorities announced an investigation into the case but since China does not have animal welfare laws they were not charged. Zhifen orally presented Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection at Department of Pathology Retreat on October 15, 2022 at 21C Museum Hotel, Durham, NC. Dr. Wang becomes the prostate cancer project leader. 248 Qianyuan Wang Photos and Premium High Res Pictures - Getty Images Images Creative Editorial Video Creative Editorial FILTERS CREATIVE EDITORIAL VIDEO 248 Qianyuan Wang Premium High Res Photos Browse 248 qianyuan wang stock photos and images available, or start a new search to explore more stock photos and images. Caught in Time: Directed by Ho-Leung Lau. https://scholars.duke.edu/individual/pub1528949. Both Wang Yu and Li Yongjun lost their jobs as a result of the human flesh search. The title of his talk was Epigenomic approaches to discover transcriptional vulnerabilities of prostate cancer. Kexin Li from Peking Union Medical College joined the lab as a postdoctoral fellow. August 2015 from China Academy of Traditional Chinese Medicine, Beijing, China. Birthplace: Shenyang, China. Here, single-atom Cu dispersed on N-doped graphene (Cu-SA/NGO) with relatively high Cu loading of 5.8 wt% was prepared for boosting the degradation of contaminants. Qianben Wang and Fuwen Yuan presented project progress at the symposium. Our laboratory is located in the School of Medicine atDuke University, and is part of Duke Pathology, Duke Cancer Institute, and National Cancer Institute (NCI) funded San Antonio-Duke University Research Center for Cancer Systems Biology(SA-Duke RCCSB). Dr. Chen received his B.Med from Tianjin Medical University in 2003 and his Ph.D. in 2008 from the Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. , Chen, Zhong, Dayong Wu, Jennifer M. Thomas-Ahner, Changxue Lu, Pei Zhao, Qingfu Zhang, Connor Geraghty, et al. Fuwens paper entitled Molecular determinants for enzalutamide- induced transcription in prostate cancer was accepted by Nucleic Acids Research. Fuwens DoD Early Investigator Research Award application was funded. Genome-wide analysis reveals positional-nucleosome-oriented binding pattern of pioneer factor FOXA1. Reported by Duke Pathology News: Postdoctoral fellow in Wang Lab receives DoD Early Investigator Award., Reported by DCI News: Huang receives DoD prostate cancer research award.. Not kidding. , Zhang, Chunpeng, Liguo Wang, Dayong Wu, Hongyan Chen, Zhong Chen, Jennifer M. Thomas-Ahner, Debra L. Zynger, et al. Yang Tao, a government prosecutor from Jiangxi province explained in Shanghais Oriental Morning Post in 2008 that human flesh searches are a necessary avenue for ordinary citizens to seek justice. Furongs DoD Early Investigator Research Award application was recommended for funding. Li Yonjun, however, apologised publically. Reported by Duke Pathology News: Hankey Selected NIH T32 Post-Doc Training Program. Bills paper entitled Prostate cancer cell phenotypes remain stable following PDE5 inhibition in the clinically relevant range was the most downloaded Translational Oncology article in 2020. PBMC DNAm profiling suggests a mechanism whereby n-3 PUFAs may impact inflammatory cascades associated with disease processes including carcinogenesis. In 1997, she became the first woman to be elected as a prime minister in China. Our center PIs and postdocs including Drs. , Carroll, Jason S., Clifford A. Meyer, Jun Song, Wei Li, Timothy R. Geistlinger, Jrme Eeckhoute, Alexander S. Brodsky, et al. Our data elicit a pioneer and master dual role of GATA2 in mediating nucleosome dynamics and enhancing downstream signaling pathways. They often turned on their neighbours, teachers and even family in a brutal campaign against bad class elements. There is, however, a clear difference between the Red Guards and human flesh search engines; the former often knew the individuals they accused, violently attacked and sometimes killed them; the latter are usually searching for offending but personally unknown individuals and then possibly take online action, using words rather than physical assault. Qianben Wang Laboratory is powered by WordPress at Duke WordPress Sites. Wang's daughter, Wang Qianyuan, more widely known since the incident at Duke University by her English name of Grace Wang, was criticized by her fellow Chinese students for siding with "Free Tibet" supporters. , Hankey, William, Zhong Chen, and Qianben Wang. While her video post may have been inappropriate and deeply offensive to many, the case illustrates the serious nature of the searches and their possible consequences. There are 60+ professionals named "Qianyuan Wang", who use LinkedIn to exchange information, ideas, and opportunities. Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence. Police has not received any accusations," said officer Liu. Will it work in people? In this case, the human flesh search amounted to mass harassment. September 2013 Welcome, Kathryn! We quantitatively define nine functional nucleosome states each with specific characteristic nucleosome footprints in LNCaP prostate cancer cells. Chinese human flesh search engines are examples of netizen vigilantism. Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer. , Wang, Hongyan, Chunpeng Zhang, Anna Rorick, Dayong Wu, Ming Chiu, Jennifer Thomas-Ahner, Zhong Chen, et al. Three-tiered role of the pioneer factor GATA2 in promoting androgen-dependent gene expression in prostate cancer. "Wang refused a meeting with the police on matters of individual harassment outside his apartment. Her current research focuses on studying the epigenetic mechanisms underlying the neuroendocrine prostate cancer. Qianbens proposal was recommended for funding by Department of Defense Prostate Cancer Research Program (Idea Development Award Established Investigators). https://pathology.duke.edu/news/wang-co-organizes-san-antonio-duke-cancer-systems-biology-symposium, News on U54 website: http://molecularmedicine.uthscsa.edu/CSBC_U54.aspx, Our San Antonio-Duke University Research Center for Cancer Systems Biology proposed session Systems Epigenetics in Hormone-Driven Cancers was selected by the 2019 AACR Program Committee as a Major Symposium.